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The Science

Built on peer-reviewed
methodology.

Redundancy Analysis. Eigenvalue decomposition. Architecture-level speed. Full validation.

Redundancy Analysis

RDA is a constrained multivariate ordination method that decomposes genomic variation into components explained by environmental predictors. It identifies which allele combinations are under selection by specific climate pressures — without requiring phenotypic observation.

The method projects both genotype space and environment space onto shared canonical axes. The distance between a query genotype's projection and the environmentally-predicted optimum is the genomic offset — a continuous, interpretable measure of maladaptation risk.

Published in Molecular Ecology and Nature Climate Change. Used operationally by UC Davis, CSIC, and IRTA. The scientific foundation is established and peer-reviewed.

Why RDA over alternatives

Gradient Forest and BayPass are widely cited but are batch-only tools — designed for population-level analysis, not real-time query prediction. RDA's linear algebra structure allows the separation of model fitting from projection. This is the architectural insight that makes sub-millisecond inference possible.

RDA Projection — Spain Model
Training: 200 samples · 5 SNPs · 4 ecotypes
Axis 1: 61.3% · Axis 2: 34.7% · Total: 99.98%

The Architectural Innovation

Standard RDA implementations run as batch scripts: load data, fit model, predict, repeat. Each query triggers a full model recomputation. For 10,000 varieties, that is 10,000 full RDA fits.

YOURTIMEONEARTH permanently separates model fitting from projection. Train once on your germplasm collection. The eigenvalue decomposition is stored — not the computation, the result.

Every subsequent prediction is pure matrix multiplication on pre-computed canonical axes. No refitting. No iteration. No overhead. The projection is deterministic and takes the same time regardless of training set size.

This is an architecture-level speed gain, not an optimisation-level one. The result is 0.015 milliseconds per prediction — seven orders of magnitude faster than a field trial confirmation.

Traditional RDA

Minutes
per variety, per environment. Full model refit each time. Not suitable for real-time query.

Batch Optimised

Seconds
per batch. Pre-fit, vectorised. Suitable for offline analysis. Not suitable for API deployment.

YOURTIMEONEARTH

0.015 ms
per query. Eigendecomposition stored. Pure matrix projection. API-native. Scales to any volume.

Validation Results

0.015ms
Per prediction
8/8
Tests passed
99.98%
Variance explained
12
Locations validated
4
Climate ecotypes
Independent Validation Tests
Test Genotype Environment Offset Result
Galicia → Atlantic Galicia ecotype A Coruña · 14°C, 1000mm, pH 6.0 0.020 Highly Suitable
Galicia → Semi-arid Galicia ecotype Sevilla · 25°C, 500mm, pH 7.8 0.809 Avoid
Andalucía → Semi-arid Andalucía ecotype Almería · 22°C, 200mm, pH 8.0 0.031 Highly Suitable
Andalucía → Atlantic Andalucía ecotype A Coruña · 14°C, 1000mm, pH 6.0 0.887 Avoid
Gradient monotonicity All ecotypes All 12 locations Confirmed Pass
Confidence calibration 3-factor scoring Training size · Variance · Offset Validated Pass
Mediterranean ecotype Mediterranean ecotype Barcelona · 18°C, 600mm, pH 7.0 0.139 Highly Suitable
Continental ecotype Continental ecotype Madrid · 15°C, 400mm, pH 7.2 0.050 Highly Suitable
Confidence Scoring

Every prediction carries a confidence score derived from three independent factors: training set size (more samples → higher confidence), variance explained by the RDA model (higher R² → more reliable), and offset magnitude (extreme values reduce confidence as they are further from the training distribution). The Spain model achieves 99.98% variance explained, placing it in the highest reliability tier.

Methodology References

Peer-reviewed foundations
·
Forester et al. (2018) Molecular Ecology — Redundancy Analysis for local adaptation detection and genomic offset. Establishes RDA as the methodological standard for landscape genomics.
·
Fitzpatrick & Keller (2015) Ecology Letters — Genomic offset under climate change scenarios. Defines the offset statistic and its ecological interpretation in the context of maladaptation.
·
Rellstab et al. (2015) Molecular Ecology — A practical guide to environmental association analysis in landscape genomics. Provides methodological validation and comparison framework.
·
Capblancq & Forester (2021) Methods in Ecology & Evolution — Gradient Forest and RDA benchmarking. Confirms RDA's performance advantages for the specific application of climate-genomic offset prediction.

The model is trained. The platform is operational.

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